Free Classifieds Health & Fitness Fitness Equipment
Well, if ou'd like toward investigate innovative developer shirts or dresses or perhaps handbags, ou need to opt for Eastpak. A real just who potential customers marketplace becomes necessar their particular passport, airfare tickets not to mention getting on hands within eas reach. Should ou be needed for a real teleshopping firm ou ma then have fun with the having access to vinl envelope.
Just about ever invitees along with tourist whatever the him / her age group in addition to him / her interpersonal reputation create a desirable hot underwear gift idea with the oung woman. You ma decide on Meters with Eliza Kors if ou need a cutting edge sections.
A greater number of can market those bags over the internet because the view the terrific need and also imagine it is ones own obligation being a homeowner of these u . s . in order to pass on an reall enjo and get awa from rioting with the alles.
The fact is, Doone as well as Bourke items are actuall famous more and more from Hollwood's highest qualit the famous people have been seen using our handbags. There is marvelous stages of Prada Pelham wholesale handbags for sale.
Even so ou can't predict. Set up convinced ou might be crstal clear with each of our purpose.
All these tag ensure that the suitcases will be restricted firml. (The person needs trusted our man definitel, but I developed m ver own ideas recognized concerning this) Port is right now looking at Said as a crictall ill customer. Anne hathawa can readil prove the greatness of all the Teacher categor of hand bags.
The financial benefits are often extremel vital. Tpicall, the grade of something can be discovered with our buck. If ou're going to make use of Solidea Gold Wave Midriff Music band commonl, ou might experience the variance. Dance shoes are built in a couple of standard kinds, especiall those with enclosed tip toes and those with open, or sandals jamaica resorts.
Gem earrings seem to be forever functional, and ou can now bu a lot of fabulous, advanced choices to our own grandma's orbs.
Saturda was initiall rec center after which later we all did much of our 1st geo-caching affair at the talk about store. Stunning and then memorable can be ke phrases which were identified in the fragrance and also label.
Recclable getting plastic bags, b wa of example PP weaved not to mention absolutel no weaved hand bags in addition to kinds of organic-based carriers, happen to have been successful big all through worldwide recognition during two ears. That step usuall requires on the subject of 1-2 hrs which has no rest stops.
It is best to possess a artist case along with great pride.
With the ver little handbag supplier the fact that launched when i was ounger, the also have possibl developed towards a new coerce associated with strateg, through a lot of stles for designer handbags along with trainers similar. When it's result ou could be subsequent to, ou ma consider vibrant colors and additionall stunning printing.
An excellent carrier with regard to phsical what things to come to be procured along the length of can be a Handbags. You should find just what most people in search of or ou'll come across something which better et! Red or white wine ou have plent of time to find out all ou seeking for-sometimes, to as tr taking a little little bit of browse.
Ad Listed On: Sep 16, 2012
Ad Views: 39
Location: Eugene Eugene GW
Tags: fitness equipment classifieds, health & fitness advertisement
LONDON (AP) ? British police arrested a journalist Saturday on suspicion of bribery, acting on information supplied by Rupert Murdoch's News Corp.
The 43-year-old man was arrested in London by officers from Operation Elveden, which is investigating inappropriate payments to police and public officials, police said. He was freed on bail several hours later.
The corruption probe is running alongside investigations into phone hacking and computer hacking sparked by revelations that reporters at Murdoch's now-shuttered News of the World tabloid routinely intercepted voicemails of those in the public eye.
Police said Saturday's arrest ? the 47th of the investigation ? was the result of information from a News Corp. committee created to get to the bottom of the criminality at Murdoch's British newspapers.
Several people have been charged over the scandal, including former Murdoch executive Rebekah Brooks.
THG is counting down the 100 Hottest Bikini Bodies of 2012!
From now until the end of the year, we'll be paying tribute to the hottest of the hot with bikini photos galore. The competition is guaranteed to be sweltering.
Keeley Hazell bikini pictures were honored yesterday as this very smoldering countdown continued. Keeping the hotness rolling today at #85: Joanna Krupa!
The Assassins of Te'i Sai have begun to move, and the land is drenched in blood. Do you have what it takes to survive this epic battle of stealth, power and deceit?
Owner:
Game Masters:
Topic Tags:
Forum for completely Out of Character (OOC) discussion, based around whatever is happening In Character (IC). Discuss plans, storylines, and events; Recruit for your roleplaying game, or find a GM for your playergroup. http://piratepad.net/7dQYYfEBk2
This site is a chat pad which we can use to im and talk in more real-time-ishness. Haha. Anyway, I look forward to seeing you guys there!
I'm usually online from about 9pm onward each night so I'll have that window open and be there to chat with you if you drop by.
Toodles!
KumoriRyuu
Member for 2 years
Post a reply
RolePlayGateway is a site built by a couple roleplayers who wanted to give a little something back to the roleplay community. The site has no intention of earning any profit, and is paid for out of their own pockets.
If you appreciate what they do, feel free to donate your spare change to help feed them on the weekends. After selecting the amount you want to donate from the menu, you can continue by clicking on PayPal logo.
ScienceDaily (Sep. 12, 2012) ? Researchers from Trinity College Dublin have recently shown that the legs of grasshoppers and crabs have the ideal shape to resist bending and compression. If human leg bones were built the same way, they could be twice as strong.
"Like all Arthropods, grasshoppers and crabs have so called exoskeletons made from a very special material called cuticle," said Professor David Taylor, of the Trinity Centre for Bioengineering at Trinity College Dublin, Ireland. "This exoskeleton protects the animal like a knight's suit of armour. Recently we have shown that this cuticle is in fact one of the toughest natural materials."
"In terms of evolution, having your bones on the outside has been a pretty good concept," said his colleague Dr Jan-Henning Dirks. "Since millions of years animals with exoskeletons such as insects, spiders and crustaceans can be found basically in every ecosystem in the world."
So what makes this exoskeleton so successful? Together the interdisciplinary team used the latest principles of engineering mechanics, materials science and biomechanics to address this question. In particular, Taylor and Dirks were interested in the diameter and thickness of the bones. They used a special computer-tomography machine to generate X-ray images of insect legs with a resolution of only a few thousands of a millimetre and collected and compared data from crabs and human bones.
Their results, published in the article 'Shape Optimisation in Exoskeletons and Endoskeletons: a Biomechanics Analysis' in the Journal of the Royal Society, Interface, showed that, whilst human leg bones are relatively thick-walled tubes, the legs of insects and crabs have a much thinner wall in relation to their radius.
"This relation of wall-thickness to radius can tell us a lot about the mechanical stability of the structure," said Taylor. "Imagine the bones as simple tubes. Now, if you had a limited amount of material, what would you do? Would you make a thin solid rod or a hollow, thin walled tube? When compressed, the rod might easily bend like a straw, the hollow tube however might buckle like a beer-can."
However, for a given weight there is a mechanical optimal wall-thickness. And interestingly, the researchers found that the leg-shape of crabs represents an ideal compromise to resist both the bending and compression forces the crab experiences when walking under water.
The locust leg on the other hand is optimised to withstand the huge bending forces which occur when it jumps.
In comparison, the human thighbone didn't do so well. Using the same amount of bone material and taking into account its mechanical properties, the human thighbone could be "redesigned" as an exoskeleton to be twice as strong as it is now.
"Of course there are numerous other factors determining the evolutionary advantages of endo- and exoskeletons," said Taylor. "However, we think that by taking a design engineer's view on the problem we've been able to shed some light on the evolutionary development of skeletal forms."
Share this story on Facebook, Twitter, and Google:
Other social bookmarking and sharing tools:
Story Source:
The above story is reprinted from materials provided by Trinity College Dublin, via AlphaGalileo.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
D. Taylor, J.-H. Dirks. Shape optimization in exoskeletons and endoskeletons: a biomechanics analysis. Journal of The Royal Society Interface, 2012; DOI: 10.1098/rsif.2012.0567
Note: If no author is given, the source is cited instead.
Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.
Childrem of immigrants come out ahead of peersPublic release date: 13-Sep-2012 [ | E-mail | Share ]
Contact: Amy Lunday acl@jhu.edu 443-287-9960 Johns Hopkins University
Children of immigrants are outperforming children whose family trees have deeper roots in the United States, learning more in school and then making smoother transitions into adulthood, according to sociologists at The Johns Hopkins University.
Researchers Lingxin Hao and Han S. Woo tracked nearly 11,000 children from as young as age 13 into their early 30s, coming from families with diverse backgrounds. When comparing children with similar socioeconomic status and school conditions, Hao and Woo found that the best students, and later the most successful young adults, were born in foreign countries and came to the United States before reaching their teens. American-born children whose parents were immigrants followed closely in terms of achievement.
Hao and Woo found that the advantages were comparable for both Asian and Hispanic children. Their study, "Distinct Trajectories in the Transition to Adulthood: Are Children of Immigrants Advantaged?" appears as part of a special section on children from immigrant families in the September/October 2012 edition of the journal Child Development.
The study affirms the ideal of the American immigrant success story at a time when immigration is often seen as a problem. Today, almost one quarter of American children are the children of immigrants, based on Census Bureau's American Community Survey 2009, so this study suggests good things for the quality and skill level of the U.S. labor force down the line, said Hao, the study's lead author.
"Our findings challenge the view that children of immigrants are lagging behind children of native-born parents in the transitioning to adulthood," said Hao, a professor of sociology in the Krieger School of Arts and Sciences at Johns Hopkins. "Given the same backgrounds, children of immigrants are actually more likely to follow the best trajectory leading to positive early adult outcomes."
Hao and Woo, a graduate student, followed data linked to individual children from ages 13 to 17 up to ages 25 to 32. The researchers set out to see which groups of children followed the best trajectory in terms of academic achievement, which Hao and Woo measured by the level of difficulty in the math and science courses the students completed. They also looked at school engagement, or the proportion of courses each high schooler passed in an academic year, assuming that if students were engaged in their work, they should pass every class.
To measure success when the subjects reached their 20s and 30s, Hao and Woo looked at the level of the highest academic degrees attained and general psychological well-being using a scale based on feelings of social belonging, control of life circumstances and confidence in handling personal problems.
What explains the more positive trajectory for children of immigrants? Hao suggests that there is a greater sense of community among immigrants out of necessity: Newcomers often need a lot of assistance when they first arrive in the United States. But Hao, who is from China, thinks there is also a great deal of inspiration to be found among the immigrant community. Parents, she says, might be working multiple low-level jobs and encourage their children to seek a better life for themselves. The success stories of immigrants who have "made it" are also held up as role models for immigrant children, something children of native-born parents might be lacking, Hao says. To that end, this research can inform education and labor-force policy makers when it comes to new plans to help lower socioeconomic groups move ahead, she says.
"With 24 percent of all American children from immigrant families, our findings provide fresh evidence for policymakers who are concerned with the quality of immigrant generations and the skill composition of the future labor force," Hao said. "My hope is that policymakers will look at our findings and work on ways to create similar 'protective factors' for all racial minority children, because these factors allow children from immigrant families to do well and be resilient despite their lower socioeconomic and racial-minority backgrounds."
Hao and Woo analyzed data from the National Longitudinal Study of Adolescent Health and the Adolescent Health and Academic Achievement study, both funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development. The current study was funded by an NICHD training grant to the Johns Hopkins University Population Center, founded in 1971 to stimulate and facilitate interdisciplinary population research throughout the university.
###
Related links:
Child Development article:
http://onlinelibrary.wiley.com/doi/10.1111/j.1467-8624.2012.01798.x/full
The Child Development special section:
http://onlinelibrary.wiley.com/doi/10.1111/cdev.2012.83.issue-5/issuetoc#group2
Johns Hopkins University Population Center:
http://web.jhu.edu/popcenter
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Childrem of immigrants come out ahead of peersPublic release date: 13-Sep-2012 [ | E-mail | Share ]
Contact: Amy Lunday acl@jhu.edu 443-287-9960 Johns Hopkins University
Children of immigrants are outperforming children whose family trees have deeper roots in the United States, learning more in school and then making smoother transitions into adulthood, according to sociologists at The Johns Hopkins University.
Researchers Lingxin Hao and Han S. Woo tracked nearly 11,000 children from as young as age 13 into their early 30s, coming from families with diverse backgrounds. When comparing children with similar socioeconomic status and school conditions, Hao and Woo found that the best students, and later the most successful young adults, were born in foreign countries and came to the United States before reaching their teens. American-born children whose parents were immigrants followed closely in terms of achievement.
Hao and Woo found that the advantages were comparable for both Asian and Hispanic children. Their study, "Distinct Trajectories in the Transition to Adulthood: Are Children of Immigrants Advantaged?" appears as part of a special section on children from immigrant families in the September/October 2012 edition of the journal Child Development.
The study affirms the ideal of the American immigrant success story at a time when immigration is often seen as a problem. Today, almost one quarter of American children are the children of immigrants, based on Census Bureau's American Community Survey 2009, so this study suggests good things for the quality and skill level of the U.S. labor force down the line, said Hao, the study's lead author.
"Our findings challenge the view that children of immigrants are lagging behind children of native-born parents in the transitioning to adulthood," said Hao, a professor of sociology in the Krieger School of Arts and Sciences at Johns Hopkins. "Given the same backgrounds, children of immigrants are actually more likely to follow the best trajectory leading to positive early adult outcomes."
Hao and Woo, a graduate student, followed data linked to individual children from ages 13 to 17 up to ages 25 to 32. The researchers set out to see which groups of children followed the best trajectory in terms of academic achievement, which Hao and Woo measured by the level of difficulty in the math and science courses the students completed. They also looked at school engagement, or the proportion of courses each high schooler passed in an academic year, assuming that if students were engaged in their work, they should pass every class.
To measure success when the subjects reached their 20s and 30s, Hao and Woo looked at the level of the highest academic degrees attained and general psychological well-being using a scale based on feelings of social belonging, control of life circumstances and confidence in handling personal problems.
What explains the more positive trajectory for children of immigrants? Hao suggests that there is a greater sense of community among immigrants out of necessity: Newcomers often need a lot of assistance when they first arrive in the United States. But Hao, who is from China, thinks there is also a great deal of inspiration to be found among the immigrant community. Parents, she says, might be working multiple low-level jobs and encourage their children to seek a better life for themselves. The success stories of immigrants who have "made it" are also held up as role models for immigrant children, something children of native-born parents might be lacking, Hao says. To that end, this research can inform education and labor-force policy makers when it comes to new plans to help lower socioeconomic groups move ahead, she says.
"With 24 percent of all American children from immigrant families, our findings provide fresh evidence for policymakers who are concerned with the quality of immigrant generations and the skill composition of the future labor force," Hao said. "My hope is that policymakers will look at our findings and work on ways to create similar 'protective factors' for all racial minority children, because these factors allow children from immigrant families to do well and be resilient despite their lower socioeconomic and racial-minority backgrounds."
Hao and Woo analyzed data from the National Longitudinal Study of Adolescent Health and the Adolescent Health and Academic Achievement study, both funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development. The current study was funded by an NICHD training grant to the Johns Hopkins University Population Center, founded in 1971 to stimulate and facilitate interdisciplinary population research throughout the university.
###
Related links:
Child Development article:
http://onlinelibrary.wiley.com/doi/10.1111/j.1467-8624.2012.01798.x/full
The Child Development special section:
http://onlinelibrary.wiley.com/doi/10.1111/cdev.2012.83.issue-5/issuetoc#group2
Johns Hopkins University Population Center:
http://web.jhu.edu/popcenter
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
SALMON, Idaho (Reuters) - Smoke from a massive Idaho wildfire posed a health risk to a small mountain town that was the staging area for firefighters battling the blaze, health officials said on Tuesday.
Government air monitors showed pollution levels peaked in the hazardous zone Monday night as the Mustang Complex fire, north of Salmon in east-central Idaho, poured thick smoke into a community that has coped with poor air for nearly seven weeks.
"I think we all have to consider it a crisis at this point," said Jim Vannoy, program manager for environmental health education and assessment with the Idaho Department of Health and Welfare.
The lightning-sparked blaze that has raged since late July is one of several large fires in the West.
Idaho's Mustang Complex in the Salmon-Challis National Forest grew to nearly 300,000 acres on Tuesday as firefighters braced to defend homes in two small communities. About 400 residences were ordered evacuated on Sunday.
In neighboring Washington state, 100 smaller wildfires from the Washington-Oregon line to just west of Spokane and north to the Canadian border charred 80,000 acres, threatening scores of homes, officials said.
In Idaho, relief from the smoke was not expected any time soon. The smoke contains noxious gases like carbon monoxide and fine particles that can drive deep into the lungs and aggravate or cause respiratory or heart ailments.
Public health experts said research is limited on the long-term effects of wildfire smoke because the exposure usually is concentrated in remote, sparsely populated areas.
"In general, the thoughts are that the health effects will be resolved because the events are, at most, weeks in duration," said Joel Kaufman, professor of environmental and occupational health at the University of Washington.
Janet Nelson, local emergency services coordinator, said she was fielding reports of children coughing to the point of vomiting, health workers complaining of fatigue and scores of people with persistent headaches.
"I have worries for the health of the community," she said.
County emergency managers provided residents with masks on Tuesday. Nelson said her office had dispensed nearly 300 masks and school officials urged students to wear them.
"I feel like I'm a smoker - and I don't smoke," said Kellen Miller, a 26-year-old science teacher, describing nights of disrupted sleep and work days made difficult by headaches.
In Washington state, about 2,500 firefighters, helped out by 150 minimum-security prison inmates, were able to hold most fires in the state at bay. State Department of Natural Resources spokesman Bryan Flint said shifting winds due on Thursday could cause problems.
The most threatening blaze, the Canyons Fire, a mile west of Wenatchee, merged with the Twin Peaks fire on Tuesday. It burned 1,200 acres and prompted evacuation of 150 homes.
(Additional reporting by Laura L. Myers in Seattle; Editing by Cynthia Johnston and Stacey Joyce)
FLORHAM PARK, N.J. (AP) ? Tim Tebow ran out onto the field for the New York Jets' first offensive play of the season as a starter.
Not at quarterback, of course. That's Mark Sanchez's job. But in his Jets debut last Sunday, there was Tebow lined up on the right side of the line as a slot receiver ? officially listed as a tight end.
The crowd cheered, Tebow ran a harmless route and then headed back to the sideline. A sprinkling of Tebow and the wildcat package turned out to be more than enough in a 48-28 rout of the Bills.
"I'm definitely competitive, but the No. 1 thing to help competitiveness is winning football games," said Tebow, who was involved in only 10 of the Jets' offensive snaps. "However I can help this team to win football games, that's the ultimate goal."
That's coming from a guy who has always expressed a desire to be a starting quarterback in the NFL, and led Denver to the playoffs in that role after earning the job last season.
With the Jets, at least through the first game, he's merely a contributor who ran five times for 11 yards and didn't throw a pass. But he's a player who gives opponents fits because they have to plan for him, regardless. That includes Pittsburgh, which might see Tebow maybe as little as Buffalo did. Steelers coach Mike Tomlin knows better, though, than to brush off Tebow's presence.
"That's something that they control, from a play-calling standpoint," Tomlin said Wednesday. "I know that we better be prepared for more than what I saw him do in the game on Sunday."
After all, Tomlin and the Steelers have seen him do a lot more. Tebow knocked them out of the playoffs last season with an 80-yard touchdown pass to Demaryius Thomas in overtime in Denver last season.
"Obviously, he's a capable passer," Tomlin said. "That's an element of it that we need to be prepared for."
And that is exactly why the Jets ? particularly coach Rex Ryan, general manager Mike Tannenbaum, offensive coordinator Tony Sparano and owner Woody Johnson ? wanted Tebow on their team.
Some have said New York's trade for the quarterback in March was purely a publicity stunt. The Jets have said it makes them a better offense, one with an unpredictable presence that might be unmatched in the entire league. After all, Tebow is a 6-foot-3, 250-pound, rock-solid guy who can run it, toss it or throw a block ? as he did on a few special teams plays last week.
The element of surprise is part of the playbook, and one that can't be overlooked. Just because the Jets used him sparingly in Week 1 doesn't mean there won't be a whole lot of Tebow Time this Sunday at Pittsburgh, or next week at Miami, and so on.
"We're never going to put a number out there," Ryan said of what percentage of plays made for Tebow were used against the Bills. "We're going to leave it as is. It will always be in the game plan. We'll see how much we need to use it, how little we'll do and how much we'll do. It'll obviously depend on what we think is in our best interest.
"Will it vary from week to week? It probably will, but teams need to prepare for it."
Tebow ran only two true wildcat plays against the Bills, with Sanchez lined up at wideout. Most of his other snaps came out of the read-option, and for only the fifth time in his NFL career, he didn't throw a pass in a game in which he has played.
He even got surprisingly booed for the first time as a member of the Jets when he failed to gain anything on a second-and-6 play from the Bills 12. Some fans and media reasoned that it might have taken away from the rhythm Sanchez was in with the offense at that point, forcing Tebow into the mix unnecessarily.
"It's something that I've had to do before," Tebow said of his various roles. "My first year in Denver and my first four games last year, and also my freshman year at Florida, I had a role similar to this."
But he's also coming off a magical season in which he had comeback after comeback and was the starting quarterback for a playoff team.
"This is a new opportunity, a new team and I'm excited to be here," he said. "I'm not looking back at the past. I'm just trying to do the best I can with the present and look forward to the future."
Tebow has consistently said all the right things since coming to New York, refusing to add any fuel to the fire by saying he wants to be out there more or thinks he could do more. Sanchez, to his credit, has also been careful with what he has said when it comes to Tebow, and entered the season more focused than ever.
"I think he's handled everything well," Sanchez said of Tebow, whom he considers a friend. "He's really come in and fit in with our team. He's tried to be a team guy all the way. He understands that he's going to get opportunities to touch the football and when he does, he wants to make the most of them. ... If I were in his shoes, I don't know how I'd handle some of the stuff he goes through, but it's fun to talk about in the quarterbacks room."
Tebow is still undoubtedly the biggest personality on the team, and very possibly the most popular athlete in the entire New York sports scene. Whether his impact on the field matches all that hype, well, that's for opponents to find out.
From week to week, game by game.
"Whenever you get called on, you want to be able to go in there and be effective and efficient, and you want to help the team to try and get a victory," Tebow said. "You do that by creating first downs and hopefully being able to get in the end zone."
___
Follow Dennis Waszak at www.twitter.com/DWAZ73
___
online: http://pro32.ap.org/poll and http://twitter.com/AP_NFL
LONDON (Reuters) - An experimental drug that blocks certain brain receptors can reduce nicotine cravings in addicted rats and baboons - a finding researchers say could lead to new medicines to help people stop smoking for good.
The candidate drug, called GSK598809, belongs to a class of compounds that block a specific type of dopamine receptor in key areas of the brain linked to tobacco addiction.
It is now ready for testing in early-stage clinical trials in humans, said Manolo Mugnaini, a researcher at the Aptuit Centre for Drug Discovery and Development in Verona, Italy, which was formerly owned by GlaxoSmithKline.
The drug was originally being developed by GSK, but the British drugmaker decided in 2010 to end investment in some areas of neuroscience research, and halted work on GSK598809 as part of that decision. The compound is now part of a research project using imaging scans to explore brain mechanisms behind impulsivity, stress and addiction.
Previous studies have shown that nicotine in tobacco smoke increases the release of the brain chemical dopamine in the ventral striatum, midbrain and pallidum - all parts of the brain thought to play a key role in getting smokers hooked.
The World Health Organisation says there are a billion smokers worldwide and tobacco kills up to half of its users.
CRAVINGS REDUCED
Mugnaini said the animal tests as well as some very early studies in humans suggested GSK598809 blocks dopamine receptors in the brain known as D3 receptors, and helps reduce cravings.
"This is the first time with this class of drugs that we have had signals of efficacy in humans," he told Reuters.
"And what is more important about this work is that we have provided a method that can be used to take this class of compounds from pre-clinical trials to full human trials."
He said brain imaging was key to that future development.
"From our study we have pictures of the drug going to the right expected target, the D3 subtype of dopamine receptors, in brain areas that play a key role in nicotine addiction in the brain," he said.
"By following this model based on imaging of the brain, we know we can monitor the performance of the drug in humans in an efficacious way."
Mugnaini and colleagues tested GSK598809 on rats and baboons and used data from those experiments to create a model to find an appropriate dose level for humans. They then treated smokers who agreed to go without cigarettes overnight with GSK598809 and found that it partially alleviated their nicotine cravings.
More importantly, Mugnaini said, the brain imaging studies suggested that higher doses of GSK598809 than those used in the human tests may be more effective at reducing smokers' cravings.
The study's findings were published in the journal Neuropsychopharmacology on Wednesday.
Several drugs are already on the market to help smokers quit, including Pfizer's Chantix or Champix, and GSK's Zyban, an antidepressant also approved for smoking cessation.
Although there are years of testing ahead before this experimental drug may be licensed for use in patients, Mugnaini said it could one day be used alongside a drug like Chantix.
Because they have different modes of action, Chantix may be more beneficial in helping smokers take the initial step of quitting, he said, while a new drug from GSK598809's class would be designed to reduce cravings once they have stopped, limiting the risk they will relapse, a common problem for smokers.
The American Lung Association (ALA) estimates it takes the average smoker five or six serious attempts to finally quit.
Tech ? Service restored after several hours as cause investigated.
Thousands and possibly millions of websites hosted by GoDaddy.com went down for several hours on Monday, causing trouble for the mainly small businesses that rely on the service.
A Twitter feed that claimed to be affiliated with the "Anonymous" hacker group said it was behind the outage, but this couldn?t be confirmed. Another Twitter account, known to be associated with Anonymous, suggested the first one was just taking advantage of an outage it had nothing to do with.
GoDaddy spokeswoman Elizabeth Driscoll said the outage began shortly after 1 p.m. EDT. By around 5:50 p.m. EDT, the GoDaddy.com website and sites hosted by the company were back up and running. Driscoll had said the company was investigating the cause.
GoDaddy.com hosts more than 5 million websites, mostly for small businesses. Websites that were complaining on Twitter about outages included MixForSale.com, which sells accessories with Japanese animation themes, and YouWatch.org, a video-sharing site.
Catherine Grison, an interior designer in San Francisco who operates the site YourFrenchAccent.com, said she had to stop sending emails with her website link in them while the outage was ongoing. The site is where she displays her portfolio of work.
"If I have no visuals I have nothing left except the accent," said Grison, a native of Paris. She said she was already shopping around for another site host because she was unhappy with GoDaddy?s customer service.
Earlier, Kenneth Borg, who works in a Long Beach, Calif., screen printing business, said fresnodogprints.com and two other sites were down. Their email addresses weren?t working either.
"We run our entire business through websites and emails," Borg said.
The business even takes orders from its two physical stores through the Web, so clerks had to use their personal email addresses to send in orders to the printing shop, causing an administrative headache, Borg said.
story continues below
Copyright 2012 The Salt Lake Tribune. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
by Carlita Morandi Send Feedback to Carlita Morandi Request Reprint |
Print |
About Author |
Report Problem |
Tweet This
#writername#'s web site
When you are buying a new home, there are a lot of different factors and parameters that you have to consider. The first thing would be the building itself. When analyzing the building, you have to check the type of door, the windows, the design of the building, and, not to forget, the environment and the ambience as well. Thus, there are various factors that have to be considered, but it is important that you carefully analyze the type of windows that are provided. Some buildings may not have the ample amount of them, while sometimes there are buildings where there are too many windows and thus they may become difficult to handle. So, you need to carefully explore your choices and pick the best deals out of it.
Windows are one of the most essential components of your home because they bring in fresh air which is extremely important for the smooth working of your mind. It is always advisable that you regularly open your windows for some time as it leads to efficient air circulation and brings in new and positive energy into our body. So, you need to have the right type of window in your home. If yours have come out of fashion, you can opt to get them replaced or if they are in a broken state, you can fix them up as well. Thus, the choice is yours. However, no matter what you choose, you should always try to fix the problems of widows at the earliest.
The style and design of windows tends to change from time to time. The type of window that was in vogue a couple of decades back is not the same as what it is today. So, you must be aware of the current fashion and trend and then you should choose accordingly. If you think that the windows in your home are not good enough as they lessen the charm of your home, you can get them replaced. If you are opting for replacement, you should first explore the ruling designs and then analyze as to whether they would match with the remaining design of your home. If the design would suit your home, you can rope in an interior designer or renovators and they would change the windows easily.
Thus, you have to be careful of a lot of factors when deciding the efficiency of the window (known in Danish as vindue) that you would want for your home. It is vital that you choose a home with the right type of windows because it helps in enhancing the beauty and charm of your place. You should not compromise with quality and design as they can aid in beautifying a place. Some of the most beautiful homes that you may have ever seen are sure to have the finest set of windows. So, look out for the types of windows while buying a new property and if your house is in need of renovation, make it a point to choose the perfect set of them as per the ruling trends. More information on the subject you can find here.
Contact the Author
Carlita Morandi
carlita.morandi@gmail.com Carlita Morandi's web site
awesome comments
Related Articles
Keywords: windows, new windows, exterior, new door, cheap windows, window manufacturer
This article has been viewed 17 time(s).
Does this article infringe on your copyright?
It is a violation of our terms and conditions for writers to submit material which they did not write and claim it as their own.
If this article infringes on your copyrights, you MUST either call us at 706-866-2295 or send proof of infringement
along with the offending article's title, URL, and writer name to
IdeaMarketers.com
Attn: Marnie Pehrson - Copyright Concern
514 Old Hickory Ln
Ringgold GA 30736 USA
If you email us or use our problem submission form, we CANNOT guarantee we'll receive your notice!
Okay, it's a little too late for Johnny 5's grass hopper, but thanks to new "gentle" robotic tentacles developed at Harvard University, future generations of insects could escape a similar demise. Researchers have created a new soft appendage made from flexible plastic, that uses three compartmentalized air channels to achieve a snake-like range of movement. The touch of the tentacle is so light, that it is able to pick flowers without damage. While suggested applications include working with fragile objects, or in hard to reach locations, the team also experimented by adding cameras, suction cups and -- most terrifyingly -- syringes to the tip. The only limitation, apparently, is that the air channels prevent it from being scaled down. So while our insect friends are safe from strangle-bot, we might not be so lucky.
7924 Melogold Cir, Land O Lakes, FL | Get?Directions?? $15.00
Join the ladies of Women-N-Charge for a Murder Mystery Afternoon Tea Party on October 13, 2012 from 2-4 pm. ??It will be a fun filled afternoon of tea, delicious food, networking, a hat contest, door prizes, vendor tables, goodie bags and so much more!? Tickets are just $15 for one and $25 for two. You can purchase them online at?www.Women-N-Charge.com.? All proceeds go towards WNC's annual scholarship fund for women in business.? The tea will be held at The Groves Golf and Country Club (7924 Melogold Circle, Land O' Lakes, FL 34637).? For more information contact info@women-n-charge.com.
In case you didn't notice, Microsoft and Nokia are holding a pretty major press event right now, and while we've mainly been waiting for some shiny new hardware, a few fresh apps never hurt either. Nokia just made a joint announcement with AOL, unveiling an entertainment hub called Entrance, which will be available only on Nokia's Windows Phone devices. AOL (which happens to be Engadget's parent company) naturally used the app as a way to highlight its various properties, including Moviefone, AOL Music and Huffington Post Entertainment. So, for example, you might watch trailers or buy tickets on Moviefone, or read news from HuffPo. Like its various Android apps, it includes Shoutcast Radio integration with streaming from over 55,000 radio stations worldwide. Perhaps the most compelling bit, though, is an augmented reality feature with overlays for movie posters and show times. The app's free and available for download at the source link below, and we've also got some screenshots to help give you a sense for the look and feel.
Loading...
![[ Back to EurekAlert! ]](http://www.eurekalert.org/images/back2e.gif){kind=small}
Public release date: 13-Sep-2012
Share ] 
